They should also be used to prevent motion sickness rather than treating it.
Diminishes vestibular stimulation and depresses labyrinthine function through central anticholinergic effects.
However, prolonged treatment may decrease rate of recovery of vestibular injuries.
Dextromethorphan is the most commonly used over-the-counter anti-tussive and expectorant medicine at therapeutic doses.
Due to easy availability, euphoric high and hallucinogenic effects at larger doses, dextromethorphan popularity amongst the drug abusers is growing day by day.
Due to concerns regarding their addictive potential, they are not as often prescribed.
While having been shown to have some efficacy in preventing motion sickness, these are a controlled substance with a high abuse potential, and therefore should be prescribed with caution.
Common adverse effects can include dry mouth/nose/throat, drowsiness, loss of visual accommodation, and sensitivity to bright light.
Less common adverse effects include palpitations, urinary retention, bloating, constipation, headache, and confusion.
Besides dextromethorphan other drugs of abuse like cannabinoids, opiates, benzodiazepines, ethanol and chlorpheniramine were also detected.
The cause of death was determined to be acute dextromethorphan intoxication with lethal synergistic effect of other co-ingested drugs of abuse.
Oral tablets are also available and should be taken 1 hour prior to departure at their recommended doses.