After Bicho, his reputation as an actor had been solidified and he was cast as the male lead in Abril Despedaçado (Behind the Sun), one of the nominees for best foreign film in the 2002 Golden Globe Awards.
He had another performance in the 2003 Hector Babenco film Carandiru, where he played a transsexual prisoner known as "Lady Di".
By the end of the film, he received a standing ovation from the audience.
He also went on to win the festival's best actor trophy.
Santoro was also the voice actor of the titular character in Stuart Little and its sequel in the Brazilian dubbed copies.
His first major role in a cinema production came in 2001, with Bicho de Sete Cabeças (Brainstorm) by Brazilian director Laís Bodansky.
Canadian director Robert Allan Ackerman signed Santoro for his TV production The Roman Spring of Mrs.
Stone after being mesmerised by his performance in Bicho de Sete Cabeças.In 1993, as Santoro was studying Journalism at PUC-Rio, he entered the Actor's Workshop of Rede Globo.Santoro went on to play parts in many of Globo's telenovelas, such as Olho no Olho (1993), Pátria Minha (1994), Explode Coração (1995), O Amor Está no Ar (1997), Suave Veneno (1999) and Mulheres Apaixonadas (2003), as well as the miniseries Hilda Furacão (1998), in the role of a priest.She's certainly had her fair share of hunky suitors through the years.Even on its release there were some grumblings about Curtis’ privileging of grand romantic gestures over character development.Super-much." That brings us to 2009, when Portman and Millepied met on the set of "Black Swan," where he worked as Portman's choreographer and on-screen dance partner in the ballet film.